Saturday, May 23, 2020

Legal Cannabis Hemp Oil Effectively Treats Chronic Neuropathic Pain



Researchers at The University of New Mexico in a recent study examined the effectiveness of consuming hemp oil extracted from the whole Cannabis plant using a chronic neuropathic pain animal model. In the study, researchers showed that legal Cannabis hemp oil reduced mechanical pain sensitivity 10-fold for several hours in mice with chronic postoperative neuropathic pain.

Distinguished from its still largely criminally prohibited cousin, “hemp” refers to Cannabis plants with less than 0.3 percent tetrahydrocannabinol (THC) per mass. Hemp is now federally legal to produce and consume in most regions throughout the United States (U.S) as a result of the Hemp Farming Act, proposed by the U.S. Congress and signed into law by President Donald Trump in 2018.

This major breakthrough in cannabis prohibition now enables millions of Americans the ability to access a natural, effective, and relatively safe alternative option for treating chronic pain. Conventional pharmacological drugs, namely opioids, are driving the leading form of preventable deaths and conventional medical errors are the third leading cause of death in the U.S.

UNM researchers have found that hemp oil helps to reduce pain in mice.

Credit: University of New Mexico

The University of New Mexico has conducted a series of recent studies testing the effectiveness and safety of consuming the Cannabis plant, but this is the first study measuring the therapeutic potential of legal hemp oil with low THC levels.

“Cannabis plants with low THC are still psychoactive, but tend to result in fewer psychedelic experiences, while still offering profound and often immediate relief from symptoms such as pain, anxiety, and depression,” says co-researcher, Dr. Jacob Miguel Vigil, associate professor in the UNM Psychology Department.

Using a chronic neuropathic pain model that exposes mice to post-operative neuropathic pain equivalent to several years of chronic pain in human clinical patients, the researchers were able to examine how hemp oil influences momentary pain sensitivity to the affected region. For several hours after Cannabis consumption the mice demonstrated effective pain relief, approaching the mechanical pain sensitivity of naïve control mice that did not undergo the surgical operation.

“Our lab utilizes a unique nerve injury model mimicking human neuropathic pain that has allowed demonstration of hemp’s reversal of the pain-related behavior,” said one of the lead investigators, Dr. Karin N. Westlund, Department of Anesthesiology, their article titled “The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model,” published in the journal Life.

Studies in animals can be superior to clinical trials because they circumvent human biases and expectancy effects, or perceptual and cognitive reactions to enrollment in cannabis-themed experiments. Several studies measuring the effects of cannabis in humans observe patients reporting psychedelic experiences, whether or not they received the active cannabis agent, otherwise referred to as the ‘placebo effect.’

The study examined the effectiveness of “LyFeBaak” hemp oil, produced by Organic-Energetic Solutions, which has been available for legal purchase in New Mexico since 2019. “We grow hemp that is optimized to potentiate the plant's utmost health and vitality through hypermineralization techniques, rather than merely plants that are grown in a state of fight-or-flight, which unfortunately is common in the cannabis industry. These techniques have enabled us to produce hemp products that patients swear are effective in treating dozens of mental and physical health conditions. The new changes in hemp laws are now allowing us to test these claims,” adds co-author and hemp grower, Anthony L. Ortiz.

“Hemp plants contain numerous therapeutic constituents that likely contribute to analgesic responses, including terpenes and flavonoids, which in theory, work together like members of a symphony, often described as the entourage effect,” says fellow researcher, Jegason P. Diviant. Several clinical investigations have shown that medications based on synthetic cannabis analogs and isolated compounds tend to offer lower reported symptom relief and a greater number of negative side effects as compared to the whole plant, or “full-spectrum” Cannabis flower and plant-based extracts.

The authors do caution that few studies exist on the long-term use of hemp oil, due mostly to historical federal prohibition laws in the U.S. “However, this is an extremely exciting time in modern medical discovery, because the average citizen now has legal access to a completely natural and effective medication that can be easily and cheaply produced, simply by sticking a seed in the ground and caring for it as you would any other important part of your life,” says Vigil.

This investigation was supported in part by private donations from individuals to The University of New Mexico Medical Cannabis Research.



Contacts and sources:
Steve Carr
University of New Mexico

Publication: The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model. Jacob M. Vigil, Marena A. Montera, Nathan S. Pentkowski, Jegason P. Diviant, Joaquin Orozco, Anthony L. Ortiz, Lawrence J. Rael, Karin N. Westlund. Life, 2020; 10 (5): 69 DOI: 10.3390/life10050069

10 comments:

  1. I have been battling this Herpes disease for almost 3 year now....I tried all possible means to get cure from my Herpes Disease but all to me in vain until i saw a post in a health forum about a herbal doctor  Dr Uganloga who prepare herbal medicine to cure all kind of diseases including Herpes Disease, at first i doubted if it was real but decided to give it a try...when i contact Dr Uganloga via his email druganlogaherbalhome@gmail.com write him and reply me explain how the process work so after ordering for the medicine I got it within 3/4 working days through DHL Delivery and I took it according to the way Dr uganloga instructed, I was so happy after 2 week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative...Herpes patients should also get in touch with this herbalist Dr uganloga to get ride of these Herpes Virus forever his whatsapp number +2348107181623... 

    ReplyDelete
  2. You have done a great job I hope you will do much batter in the future https://anjun1.net/.

    ReplyDelete
  3. God bless Dr. USELU for his marvelous work in my life, I was diagnosed of HERPES SIMPLEX VIRUS since 2018 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr. USELU , how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine within 3 days. I took the medicine as prescribed by him and 2weeks later i was cured from HERPES contact him via email (dr.uselucaregiver@gmail.com) once again thanks to you Dr. USELU cure the flowing virus, contact his email or add him on whatsapp (+2349019328641) cancer cure
    diabetes cure
    ringing ear
    herpes cure
    warts cure
    HPV cure
    HIV cure
    get your ex back
    pregnancy herbal medicine
    Hepatitis

    ReplyDelete
  4. This is also a very good post which I really enjoy reading. It is not everyday that I have the possibility to see something like this. weed near me

    ReplyDelete
  5. Thanks for writing such a good article, I stumbled onto your blog and read a few post. I like your style of writing... Hemp

    ReplyDelete
  6. It is very good, but look at the information at this address. Hemp

    ReplyDelete
  7. I also wrote an article on a similar subject will find it at write what you think. Hemp

    ReplyDelete
  8. At this point you'll find out what is important, it all gives a url to the appealing page: Hemp

    ReplyDelete
  9. Profit primarily prime quality items -- you can understand them all within: Hemp

    ReplyDelete
  10. I encourage you to read this text it is fun described ... Pokerduit

    ReplyDelete