Wednesday, May 22, 2019

CBD Reduces Epileptic Seizures in Dogs Says "Promising and Exciting" Study

Promising and exciting. Those are the words used by Dr. Stephanie McGrath to describe findings from a pilot study to assess the use of cannabidiol, or CBD, for dogs with epilepsy.

McGrath, a neurologist at Colorado State University's James L. Voss Veterinary Teaching Hospital, led a small study with 16 pet dogs to assess the short-term effect of CBD on seizure frequency.

Based on her research, McGrath found that 89 percent of dogs who received CBD in the clinical trial had a reduction in the frequency of seizures. Nine dogs were treated with CBD, while seven in a control group were treated with a placebo.

Dr. Stephanie McGrath led a small study with 16 pet dogs to assess the short-term effect of CBD on seizure frequency.

Credit: John Eisele/Colorado State University

The research took place from 2016 to 2017, and results are published in the June 1 issue of the Journal of the American Veterinary Medical Association.

Idiopathic epilepsy, which occurs with no known cause, affects up to 5.7% of the pet dog population worldwide, making it the most common canine neurologic condition.

Dogs enrolled in the clinical trial were randomly assigned to the treatment or placebo group. Those in the treatment group received CBD oil for 12 weeks. All of the dogs were required to stay on standard anticonvulsant drugs, including phenobarbital and potassium bromide. The dogs' owners and CSU medical staff did not know if the animal received CBD or a placebo until the study was complete.

The CBD product used in the study was derived from a hemp plant, which has 0.3 percent or less of the psychoactive component of cannabis, THC. The compound is not considered marijuana and can be used for research purposes based on the 2014 United States Department of Agriculture Farm Bill.

Findings highlight effect of CBD oil on seizure reduction

In addition to the distinct reduction of seizures in the group of dogs that received CBD oil, McGrath saw a significant association between the degree of seizure reduction and the amount of CBD concentration in the dog's blood.

Based on her research, Dr. McGrath found that 89 percent of dogs who received CBD in the clinical trial had a reduction in the frequency of seizures. Nine dogs were treated with CBD, while seven in a control group were treated with a placebo.

Credit: John Eisele/CSU Photography

"We saw a correlation between how high the levels of CBD were in these dogs with how great the seizure reduction was," McGrath said.

This finding led the neurologist to adjust the dose of CBD oil for dogs in a current clinical trial, which was launched in January 2018 and aims to enroll 60 client-owned dogs with epilepsy.

McGrath described the ongoing research as exciting and important.

"It's really exciting that perhaps we can start looking at CBD in the future as an alternative to existing anticonvulsive drugs," she said.

The published study was funded by Applied Basic Science Corporation, the company that produced the CBD-infused oil evaluated in the study. McGrath has a 5% ownership in the company.

The new clinical trial is funded by the AKC Canine Health Foundation.

McGrath hopes to launch another study later this year to better zero in on the optimal dose of CBD to treat epilepsy in dogs.

Contacts and sources:
 Mary Guiden 
Colorado State University

Citation: Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy  Stephanie McGrath DVM, MS; Lisa R. Bartner DVM, MS; Sangeeta Rao BVSc, PhD; Rebecca A. Packer DVM, MS and Daniel L. Gustafson PhD  Journal of the American Veterinary Medical Association June 1, 2019, Vol. 254, No. 11, Pages 1301-1308


  1. Seizures are due to abnormal activity in the brain. I have good CBD oil from and I am highly for the usage of CBD oil medically and even medical marijuana. To fully explain how they treat seizures would be very lengthy to answer on here. It basically improves the electrical functioning of the brain that is lacking in epilepsy patients.

  2. CBD is the best natural supplement for all pets. If you can use this cbd everyday for your pets then it is for sure that your pet can fight with different kind of diseases. As their immunity level will grow up. So, if you want then you can try cbd for dog anxiety because it will also remove all anxiety problem for dogs.

  3. People having a history of such health problems like circulate and heart problems, except schizophrenia need to completely avoid hashish.Dispensary Near Me

  4. Great post, you have pointed out some fantastic points , I likewise think this s a very wonderful website.

  5. This comment has been removed by the author.

  6. hello!! Very interesting discussion glad that I came across such informative post. Keep up the good work friend. Glad to be part of your net community.

  7. In the world of www, there are countless blogs. But believe me, this blog has all the perfection that makes it unique in all. I will be back again and again. buy magic mushrooms

  8. Thanks for a wonderful share. Your article has proved your hard work and experience you have got in this field. Brilliant .i love it reading. our site

  9. Being totally sold on neutraceuticals as being the new age error to holistic health I offer you 13 powerful reasons to consider Turmeric and CBD Oil to your arsenal. Come and check out why fear is now being created around these alternatives. buy cbd vape oil

  10. I really appreciate your work which you have shared here about cbd vape oil.The article you have shared here is very informative and the points you have mentioned are very helpful.

  11. Very well written article. It was awesome article to read. Looking for the green roads cbd gummies then, is here to guide you.

  12. Much the same as other locally established organizations, you need to make some interest initially.Hemp product manufacturers

  13. It is really good to see. There are many scientists found similar result. You can use best broad spectrum CBD tincture to reduce the uneasiness and stress. It will give your positive feedbacks. You can check here to get CB products at a comfortable rate.

  14. I’m going to study this. I’ll definitely come back. much obliged for sharing. This article gives the light in which ready to watch the present. usually a very decent one and gives in-depth data. much appreciated for this pleasant article. Liquid herbal incense


  15. Hey friend, it is very well written article, thank you for the valuable and useful information you provide in this post. Keep up the good work! FYI, please check these depression, stress and anxiety related articles:
    virat kohli favourite cricketer , The Alchemist book review

  16. Do you want to experience the real marijuana feeling with an aromatic fragrance? Then you should try liquid herbal incense once. Liquid herbal incense is synthetic marijuana that contains similar chemical components to real marijuana. If you consume liquid herbal incense then you will get a similar feeling to real marijuana with an aromatic fragrance.

  17. I prefer high-quality content, which I discovered in your article about cbd neuroprotective. The information you've provided is useful and important to us. Continue to post articles like these. Thank you very much.

  18. At this time, it's most often accustomed to deal with signs and symptoms associated with depressive disorders as well as anxiousness. Nevertheless, additional problems, such as epilepsy, joint disease, persistent discomfort, as well as seizures, show excellent possibility of using cbd moonrocks.

  19. you will need support or suggestions, write me privately.
    I interested in your implementation/use case.
    the best situs slot terbaik
    daftar bo bonanza
    Slot gampang menang

  20. It is what I was searching for is really informative. weed delivery dartmouth It is a significant and useful article for us. Thankful to you for sharing an article like this.