Saturday, June 24, 2017

Cannabinoids Suitable for Migraine Prevention Says EU Study

A study presented at the Congress of the European Academy of Neurology in Amsterdam confirmed that cannabinoids are just as suitable as a prophylaxis for migraine attacks as other pharmaceutical treatments. Interestingly though, when it comes to treating acute cluster headaches they are only effective in patients that suffered from migraine in childhood.

Germany’s recent decision to liberalise the use of cannabis for medical purposes has rekindled policy debate across Europe. While politics and health authorities continue to weigh up the pros and cons of this treatment method, researchers are constantly furthering scientific understanding of the use of cannabinoids.

Image result for cannabinoids
Credit: Wikimedia Commons

Progress was reflected in the results of a current Italian study presented at the 3rd Congress of the European Academy of Neurology (EAN). A research team led by Dr Maria Nicolodi investigated the suitability of cannabinoids as a prophylaxis for migraine and in the acute treatment of migraines and cluster headaches. 

To start with the researchers had to identify the dosage required to effectively treat headaches. A group of 48 chronic migraine volunteers were given a starting oral dose of 10mg of a combination of two compounds. One contained 19 per cent tetrahydrocannabinol (THC), and while the other had virtually no THC it had a 9 per cent cannabidiol (CBD) content. The outcome was that doses of less than 100mg produced no effects. It was not until an oral dose of 200mg was administered that acute pain dropped by 55 per cent.

In phase 2 of the study, 79 chronic migraine patients were given a daily dose of either 25mg of amitriptyline – a tricyclic antidepressant commonly used to treat migraine – or 200mg of the THC-CBD combination for a period of three months. 48 cluster headache patients also received either 200mg THC-CBD or a daily dose of 480mg of the calcium channel blocker verapamil. For acute pain, an additional 200mg TCH-CBD was administered for both types of headaches.

The results after three months of treatment and follow-up after a further four weeks produced various insights. While the TCH-CBD combination yielded slightly better results than amitriptyline (40.1 per cent) with a 40.4 per cent reduction in attacks, the severity and number of cluster headache attacks only fell slightly. When analysing use in the treatment of acute pain, the researchers came across an interesting phenomenon: cannabinoids reduced pain intensity among migraine patients by 43.5 per cent. The same results were seen in cluster headache patients, but only in those that had experienced migraine in childhood. 

In patients without previous history, THC-CBD had no effect whatsoever as an acute treatment. “We were able to demonstrate that cannabinoids are an alternative to established treatments in migraine prevention. That said, they are only suited for use in the acute treatment of cluster headaches in patients with a history of migraine from childhood on,” Dr Nicolodi summarised.

Drowsiness and difficulty concentrating aside, the side effects observed during the study were highly positive. The incidence of stomach ache, colitis and musculoskeletal pain – in female subjects – decreased.

Contacts and sources:
B&K Kommunikation

Citation: 3rd EAN Congress Amsterdam 2017, 24 - 27 June 2017, Abstract Nicolodi, et al. Therapeutic Use of Cannabinoids - Dose Finding, Effects and Pilot Data of Effects in Chronic Migraine and Cluster Headache


  1. Our Cannabis Oil is Pure and potent.Never watered down or diluted,just 100% pure cannabis oil

    extracted from top quality marijuana grown by us and other professional cultivators in

    California,laboratory tested,then offered for sale here.Our cannabis oil is packaged in 1 gram and

    3.5 gram disposable syringes for easy dispensing.If you aren't sure how to get the cannabis oil

    out of the syringe,For orders and more information,Kindly contact us on our
    phone: +18475128241

  2. I admire this article for the well-researched content and excellent wording. I got so involved in this material that I couldn’t stop reading. I am impressed with your work and skill. Thank you so much. drstrainscbd is the best Cbd Store in Orlando where you can buy quality products at wholesale price.

  3. Very well said. Get All Latest Coupon Code & Offers and Promo Code For Online Shopping Sites like Amazon, Ounass, Namshi, Footlocker etc. Desertcoupon Will Ensure You Get the Right Promo Codes, Deals & Discount E-Gift Cards. Get the latest and up-to-date coupons & cashback offers. Visit and Browse through thousands of Coupons for all your favorite brands.

  4. CBD flower for sale! High quality Hemp Flower for sale online. Miami rave Products Include CBD pre rolls, Hemp pre rolls, Medical hemp flower etc. It’s a legal premium cbd flower from the hemp plant. Visit on our website and buy hemp flower Florida now. CBD hemp buds are guaranteed to be under 0.3% delta-9 THC. Florida CBD makers say the law will both weed out bad apples and help them expand.

    Buy hemp flower Florida

  5. All my life I considered nanotechnology something beyond the real. Or normal... Are you aware that some of cbd oil manufacturers like apexxx use nanotechnology in their products to make sure that cbd penetrates your body completely and is well absorbed?

  6. Hire Photo booth in the Scotland for a wedding or party. Free delivery across the UK, and our packages are all inclusive - Contact us for a quote. Custom activations for brands, agencies and event planners. That's what we do. Hire Photo booth Now. Photo booth hire in the UK for a wedding or party. Fun and interactive photo booths for every occasion, with social media integration and incredible image quality with over 100 locations.

    Hire Photo booth

  7. Free classifieds are sites that are important tools used in advertising. This is a site that is online advertising for business opportunity, real estate, and personal publicity. It is rare that the most decisive used to develop good and classified advertising is not limited to certain goods. He works for what you are selling or marketing. This is done by submitting information about products or services using the free classified ads.

    Visit: free local classified ads

  8. The Social Media Growth is one of the Best and cheap SMM Panel in USA. If you want to grow and improve your Social Media presence like Instagram, Facebook, Twitter, YouTube, Tiktok etc then you should try our Cheapest SMM panel which help you to grow on social media. Our Cheapest SMM Panel for YouTube is also Best SMM Panel. We have a professional and Best SMM Panel ready to serve you anytime you need with instant start and amazing speed delivery.

    Best SMM panel USA

  9. Polos is the best wholesale t-shirt manufacturers in India. The best part is about fabric and stitching, we use the best method to stitch. It is best you check with your requirement polyester or cotton because there are end numbers of variety in it.

  10. Do you need Best Lahore escorts? Pakistani Escort Services provide you best Lahore escorts they will keep you company and fulfill your fantasy without any problem at any time and day. You can visit our website or call us +923054442666.

    Lahore escorts

  11. Nembutal is the brand name for pentobarbital, a potent short acting barbiturate, and was available in yellow capsules ranging from 50, to 100mg, which is supplied by Abbot Nembutal with dignity.

    Nembutal Online

  12. So do you want to Polishing to the floor? We provide floor grinding and polishing services in israel. You can CONTACT US on our website for Polishing the house. Get your floors polished by our professional team that will make your floor is spick and span.

    פוליש קריסטל

  13. Do you need Wellness Coaching services? We, TAOS Total fitness brings you the best wellness coaching services in USA. You can take customized workout program designed to your goals that works for your body. Our program prepares you to exercise safely and effectively on your own, and is built around your skill level and needs. We Also Provide online personal trainer USA. Why are you waiting? get personal training in Arkansas Now.

    Visit: Northwest Arkansas Personal Trainer

  14. Are you finding Fitnessstudio in Tuttlingen? Visit Maxxifit which is one of the best Fitnessstudio egym Tuttlingen. Visit our website or call us on 074619654633.