Saturday, July 28, 2012

Unprecedented Accuracy In Locating Brain Electrical Activity With New Device

Researchers at Aalto University in Finland have developed the world’s first device designed for mapping the human brain that combines whole-head magnetoencephalography (MEG) and magnetic resonance imaging (MRI) technology. MEG measures the electrical function and MRI visualizes the structure of the brain. The merging of these two technologies will produce unprecedented accuracy in locating brain electrical activity non-invasively.

Whole-head MEG device maps the human brain
Credit:  Aalto University

- We expect that the new technology will improve the accuracy of brain mapping of patients with epilepsy. It may also improve the diagnosis of cancer patients because the improved image contrast may facilitate the characterization of cancer tissue, says Academy Professor Risto Ilmoniemi.

- The innovative MEG-MRI device will allow brain imaging for new patients, such as those with metal implants. Also, the silent and open device will not scare children or make people feel claustrophobic. In the future, this development can also reduce costs as images can be obtained in one session rather than two, Ilmoniemi states.

The problem with MEG is that when the technique is used separately, the image accuracy can be compromised because of the movement of the brain. Also, the image it provides may not be accurate enough for precise brain surgery. In the past, it was not possible to combine high-field MRI and MEG because their magnetic fields interfered with one another. Extremely sensitive magnetic field sensors have now been developed, so scientists can now use the new low-field MRI with a magnetic field strength of only a few hundred-thousandths of that of the high-field MRI device. Fusing these two technologies produces localization accuracy that was not possible with MRI or MEG alone.

The project is coordinated by Aalto University in Finland and it includes 13 research groups from five different countries. The research project is part of the European Commission Seventh Framework Program.

Brain research is one of the areas of focus in Aalto University. Among other things, Aalto researchers use modern neuroimaging methods to examine social interaction, decision-making and the effect of cinema on the human mind. Clinically oriented research is done in close collaboration with the Helsinki University Central Hospital, where the hospital, Aalto University, and the University of Helsinki have a joint research Center, the BioMag Laboratory.

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Citation: Magnetic Resonance in Medicine:Hybrid ultra-low-field MRI and magnetoencephalography system based on a commercial whole-head neuromagnetometer

Article first published online: 17 JUL 2012
DOI: 10.1002/mrm.24413

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