Monday, December 27, 2010

New Nanosensors Measure Dextromethorphan Amount in Cough-Suppressant Drug

The rigorous efforts by the Iranian researchers led to the production of a new nanosensor at laboratory scale for the specification and measurement of the amount of a cough suppressant drug used during cold.

Dextromethorphan is a cough suppressant and reliever used for the cold patients. There are many difficulties in the specification and measurement of its amount of this medicine in pharmaceutical samples.

“The objective of this research was to present a new method for the production of a nanosensor to identify and determine the amount of Dextromethorphan in pharmaceutical samples. This method is simpler, more accurate, and more precise in measuring compared to the existing methods,” Dr. Hossein Heli, Assistant Professor of Fars Science and Research Branch of the Islamic Azad University, told the news service of Iran Nanotechnology Initiative Council.

In this research, first a nanocomposite was synthesized over a base made of carbon powder, an ionic liquid, and carbon nanotubes. Then, the synthesized nanocomposite (used as a sensor) was analyzed through various physical and chemical methods. Therefore, the electrochemical activity of the drug was studied.

“It is easy to synthesize electrodes made of carbon paste, and the electrodes have a long life and a reasonable price. On the other hand, the ionic liquids that have high ionic conduction and high catalytic activity and are thermally stable, are suitable for changing the carbon electrodes,” Dr. Heli added.

The research has been published in detail in Journal of Solid State Electrochemistry, vol. 14, pp. 1515-1523, 2010.

Source: INIC

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